Sorafenib N-Oxide

N/A

Sorafenib N-Oxide

4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide

C₂₁H₁₆ClF₃N₄O₄

480.8

>95%

Aromatics, Impurities, Amines, Heteroaromatics

Sorafenib N-Oxide is metabolite of Sorafenib (Nexavar), a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), and radioactive iodine resistant advanced thyroid carcinoma